• Two New Sites Available for Early Access to Alpharadin

    Updated: 2012-12-31 16:28:08
    There are now two new, additional sites added to the Early Access Trial of the investigational treatment known as Radium-233 or Alpharadin for men with castrate resistant prostate cancer with multiple bone metastases. This post contains the most up to date and accurate information, the clinical trials.gov site is NOT currently accurate. Additionally, there are [...]

  • Scientists use ‘virtual experiments’ to uncover missing cancer targets

    Updated: 2012-12-31 00:01:00
    Cancer Research UK-funded scientists have identified 46 previously overlooked but potentially 'druggable' cancer targets, using a powerful new online approach that allows researchers to carry out 'virtual experiments' to quickly prioritise which are the best targets for drug discovery. The findings are published in the journal Nature Reviews Drug Discovery today.

  • Tumor Boards May Not Really Impact Cancer Care

    Updated: 2012-12-30 00:19:41
    Multidisciplinary teams to plan out cancer treatment may not actually improve care or outcomes, an analysis of Veterans Affairs' data suggested.

  • Going Online for Info May Reflect a Pro-Active Stance Against Cancer

    Updated: 2012-12-29 02:23:16
    Health News Going Online for Info May Reflect a Pro-Active Stance Against Cancer Print E-mail FRIDAY , Dec . 28 HealthDay News People who seek health information on the Internet are more likely to have positive beliefs about cancer prevention , instead of having the fatalistic view that that getting cancer is a matter of luck or . fate That's the finding of a survey of nearly 2,500 U.S . adults , aged 40 to 70. Previous studies have shown that television viewing can increase cancer fatalism over time . This study examined the effects of Internet . use The researchers found that people who frequently use the Internet to find health or medical information were less likely than those who didn't use the Internet for that purpose to have fatalistic views about . cancer An especially important

  • New Raccoon Virus May Offer Clues to Human Cancer

    Updated: 2012-12-29 02:23:15
    Health News New Raccoon Virus May Offer Clues to Human Cancer Print E-mail FRIDAY , Dec . 28 HealthDay News Rare brain tumors found in raccoons in Northern California and Oregon may be linked to a new virus , according to a new study . Researchers , led by scientists from the University of California , Davis , said their findings could shed light on how viruses cause cancer in both animals and humans . Understanding how infectious agents may contribute to cancer in animals has provided fundamental new knowledge on the cause of cancer in people , Michael Lairmore , dean of the university's School of Veterinary Medicine , said in a university news release . Autopsies performed on raccoons beginning in March 2010 revealed 10 raccoons had brain tumors . Of these raccoons , nine were from

  • Survival of Obamacare' Tops List of Biggest Health News in 2012

    Updated: 2012-12-29 02:23:14
    Health News Survival of Obamacare' Tops List of Biggest Health News in 2012 Print E-mail FRIDAY , Dec . 28 HealthDay News With millions of Americans watching and waiting , the U.S . Supreme Court largely upheld the Obama Administration's health care reform legislation , making the survival of Obamacare this year's top health news . story President Barack Obama's election to a second term also solidified the 2010 Affordable Care Act as a fact in American life , with new Congressional moves against the package now deemed . unlikely But it was the Supreme Court's 5-to-4 decision in June that cleared the way for implementation of reform to proceed , Karen Pollitz , a senior fellow with the Kaiser Family Foundation in Washington , D.C . told HealthDay at the time . The U.S . Congressional

  • Genes Linked to Effectiveness of Tamoxifen for Breast Cancer

    Updated: 2012-12-29 02:23:13
    Health News Genes Linked to Effectiveness of Tamoxifen for Breast Cancer Print E-mail FRIDAY , Dec . 28 HealthDay News For breast cancer patients prescribed tamoxifen to treat their disease , genetic traits affecting an enzyme in the liver are major players in determining the impact of the hormone therapy , new research suggests . There's been debate in the scientific world for years over the role of genetic differences in the enzyme , known as CYP2D6. An estimated 5 percent to 7 percent of European and North American women have a trait that prevents the enzyme from working . properly Our findings confirm that , in early breast cancer treated with tamoxifen , genetic alterations in CYP2D6 lead to a higher likelihood of recurrence and death , Dr . Matthew Goetz , a Mayo Clinic oncologist

  • Help AdvancedProstateCancer.net stay alive

    Updated: 2012-12-28 23:04:35
    We won’t let you fight your prostate cancer alone. Our mission is simple. We are men, fighting cancer, together. We share lifesaving information about the newest treatments, best (and worst) doctors and clinical trial admissions. Our Advanced Prostate Cancer program, run by Joel, has helped several thousand men live longer and happier lives in the [...]

  • Task Force Faces Scrutiny, Controversy

    Updated: 2012-12-28 21:05:00
    The relatively anonymous United States Preventive Services Task Force came under an intense spotlight when the Affordable Care Act left decision-making on huge healthcare expenditures hanging on task force recommendations -- such as the one against routine PSA testing.

  • USPSTF Says 'No' to PSA Testing

    Updated: 2012-12-28 21:00:00
    One of 2012's controversies centered on the United States Preventive Services Task Force recommendation against PSA screening for prostate cancer in otherwise healthy men. Here is our original story; in a companion article, you'll find out what's happened since then.

  • The Need to Develop Personalized Medicine Before We Cause Great Harms

    Updated: 2012-12-28 14:56:43
    Researchers at the Harvard Medical School investigated the effect of androgen deprivation in a preclinical mouse model of stable high grade prostatic intraepithelial neoplasia induced by the loss of the PTEN tumor suppressor. They found that androgen deprivation treatment of these mice accelerated the progression to invasive disease. Shidong Jia, M.D., Ph.D. And associates found [...]

  • Cancer-Related Fatigue Often Overlooked Study Finds

    Updated: 2012-12-28 02:20:18
    , Health News Cancer-Related Fatigue Often Overlooked , Study Finds Print E-mail THURSDAY , Dec . 27 HealthDay News Too few cancer patients receive care for debilitating fatigue that can last for months or even years after treatment , a new study . finds Fatigue is a factor that not only significantly diminishes quality of life but is also associated with reduced survival , study author Dr . Andrea Cheville , a physiatrist with the Mayo Clinic Department of Physical Medicine and Rehabilitation , said in a clinic news . release The study , published in the January issue of the journal Supportive Care in Cancer included 160 lung , breast , colon and prostate cancer patients who had moderate to severe fatigue . They were asked if their oncology teams had mentioned any of the cancer fatigue

  • Tissue Study Could Reshape Advanced Prostate Cancer Treatment & Bio-Markers

    Updated: 2012-12-27 16:22:17
    A comprehensive study of prostate cancer tissue done in the UK has revealed that a completely new gene network takes over driving the cancer in men who are castrate resistant. The research was published in Cancer Cell. Researchers at the Cancer Research UK Cambridge Research Institute, at the University of Cambridge studied tissue samples from [...]

  • Cancer Research UK Reveals 2012’S Greatest Legacies

    Updated: 2012-12-27 00:01:00
    The Olympic and Paralympic Games combined are expected to leave the most significant legacy of 2012, according to a survey by Cancer Research UK.

  • Bowel cancer gene discovery cracks mystery of families with a strong history of the disease

    Updated: 2012-12-23 18:00:00
    Cancer Research UK-funded scientists have discovered that two gene faults increase the risk of bowel cancer in families with a strong history of developing the disease, who, until now, had no explanation as to why their risk was greater.

  • Proton Rad Tx Not Less Toxic

    Updated: 2012-12-21 20:30:00
    Proton radiation therapy did not reduce toxicity compared with intensity-modulated radiation therapy in men who received either radiation modality for prostate cancer, a review of Medicare data showed.

  • Mortality is Directly Related to Both Time to Recurrence and Risk Level of Prostate Cancer

    Updated: 2012-12-21 20:03:25
    Mortality prospects after a prostate cancer recurrences following a radical prostatectomy has always been assumed to be directly related to the early development of metastases. A study from Melbourne Australia indicates that men with low-risk prostate cancer have good mortality prospects even when they experience early biochemical recurrence. The first author of the study, Anthony [...]

  • World-first tissue study could re-shape future of advanced prostate cancer treatment

    Updated: 2012-12-20 17:00:00
    The first-ever comprehensive study of prostate cancer tissue has revealed a completely new gene network driving the disease in patients who have stopped responding to standard hormone treatment, according to Cancer Research UK research published today in Cancer Cell.

  • Blocking SMURFs may increase effectiveness of experimental melanoma drug

    Updated: 2012-12-20 15:42:00
    Lowering the levels of a protein called SMURF2 inside melanoma cells can boost the effectiveness of experimental drugs called MEK inhibitors, according to researchers in Manchester.

  • Acknowledging That We Need to Merge Science with Personal Preferences When It Comes to Treating Advanced Prostate Cancer

    Updated: 2012-12-19 20:40:39
    There has been much discussion about the timing of treatments now that we have new drugs available to treat advanced prostate cancer. However, today’s technology does not allow us to know what the best sequencing of these drugs to maximize their efficacy would be, so we just punt along. We do not know whether or [...]

  • Men's cancer risk to climb to one in two as research drives up survival

    Updated: 2012-12-19 00:01:00
    A man's lifetime risk of developing cancer is set to reach one in two by 2027 according to new Cancer Research UK figures released today (Wednesday).

  • Psych Patients Shortchanged on Cancer Tx

    Updated: 2012-12-18 20:15:00
    Psychiatric patients with a cancer diagnosis were more likely to have metastases and less likely to receive specialized cancer treatments compared with the general population, researchers found.

  • One in five bowel cancer patients diagnosed in an emergency

    Updated: 2012-12-18 11:07:00
    Many bowel cancer patients are first diagnosed in an emergency setting, when they have severe and potentially life-threatening conditions, figures show.

  • Dr. Sartor Announces Bayer has Requested FDA Approval of Alpharedin & He Will Join Malecare to Make a Pod Cast Upon its Approval

    Updated: 2012-12-17 14:18:40
    On Thursday evening I had the opportunity to meet Dr. Oliver Sartor from the University of Tulane. At that time he informed me that Bayer had finally submitted the required paperwork to the FDA for formal approval of radium-233 chloride. For those of you who are not familiar with Dr. Sartor, he is both an [...]

  • Study shows starving cancer cells of key nutrient slows tumour growth

    Updated: 2012-12-17 09:33:00
    Depriving cancer cells of a key amino acid dramatically cuts their ability to grow and multiply, according to a new Cancer Research UK study published in Nature.

  • Blood cell gene fault linked to breast and ovarian cancer

    Updated: 2012-12-17 00:35:00
    Scientists have linked a rare genetic fault in the immune system to an increased risk of breast and ovarian cancers.

  • Thyroid cancer cases double in 20 years

    Updated: 2012-12-14 00:01:00
    The number of people diagnosed with thyroid cancer in England has doubled since the early 1990s, according to a new report published by the National Cancer Intelligence Network (NCIN) today.

  • Lifestyle-linked diseases continue to increase globally

    Updated: 2012-12-13 17:09:00
    Diseases like cancer, heart disease and diabetes are becoming the dominant cause of death and disability globally, a landmark international study has revealed.

  • On the Horizon – Cabozantinib for the Treatment of Bone Mets in Men with Advanced Prostate Cancer

    Updated: 2012-12-13 11:19:07
    According to researchers from the University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan men with advanced prostate cancer experienced significant and rapid positive effects from an investigational treatment known as cabozantinib. In a n article published online in the Journal of Clinical Oncology (Nov. 19, 2012) approximately two-thirds of men who were treated with [...]

  • Deciding Whether to Allow CPR in People with Advanced Cancer

    Updated: 2012-12-12 23:07:34
    It is unfortunate, but some of us will approach a time when we know that the advanced prostate cancer we have been battling has gotten the better of us and will end our life in the near future. If we are admitted into the hospital we will be asked to sign a lot of papers [...]

  • Tobacco giant loses display battle

    Updated: 2012-12-12 17:51:00
    One of the world's biggest tobacco firms has lost a Supreme Court fight against a planned cigarette display ban.

  • Improved treatments for chronic myeloid leukaemia have dramatically increased survival

    Updated: 2012-12-12 00:01:00
    Survival for people diagnosed with Chronic Myeloid Leukaemia (CML) has risen by nearly half, with around 58 per cent of people surviving their disease for at least five years compared with only around 40 per cent in the late 1990s, according to a new report from the National Cancer Intelligence Network (NCIN).

  • Tumor Lysis Syndrome Common in Some Cancers

    Updated: 2012-12-11 20:39:33
    ATLANTA -- The massive death of tumor cells can ironically trigger a condition that may itself be fatal to cancer patients, and it occurs in more than 20% of patients with certain cancer types, a researcher reported here.

  • MRI-Guided Biopsy Boosts Prostate Cancer Detection

    Updated: 2012-12-11 20:39:04
    Targeted prostate biopsy with magnetic resonance imaging tripled the cancer yield compared with conventional systematic biopsies, investigators reported.

  • Some Good Morning News, Zytiga Approved by the FDA for Earlier Use

    Updated: 2012-12-11 15:31:25
    Some mornings we just wake up to great news and today is one of those mornings. The Food and Drug Administration (FDA) has just announced that they have approved Zytiga (abiraterone acetate) for use prior to chemotherapy. - This FDA announcement is an expansion of their prior approved (April 2011) for the use of Zytiga [...]

  • Inherited gene fault influences breast cancer survival

    Updated: 2012-12-11 00:01:00
    Researchers have shown that an inherited gene fault influences the chances of some women surviving breast cancer. It also increases the risk of women developing a second breast cancer. The research is published in this week's Journal of Clinical Oncology.

  • FDA OKs Zytiga for Metastatic Prostate Ca

    Updated: 2012-12-10 22:06:15
    WASHINGTON -- The FDA has expanded the indication of abiraterone acetate (Zytiga) to include treatment of late-stage metastatic castration-resistant prostate cancer prior to chemotherapy.

  • Sequencing project will map DNA of up to 100,000 patients

    Updated: 2012-12-10 15:32:00
    A new £100m project will map the DNA of up to 100,000 patients with cancer and other rare diseases.

  • High-risk women may need more frequent ovarian cancer screening

    Updated: 2012-12-07 16:15:00
    Screening women at high risk of ovarian cancer once a year may not be effective enough to spot the disease in its earlier stages, and more frequent screening may be needed for this group of women, according to new research published in the Journal of Clinical Oncology.

  • Cancer death rates fall despite a rise in diagnoses

    Updated: 2012-12-07 15:53:00
    The cancer death rate in the UK has dropped for both men and women, despite a rise in the rate of people diagnosed with the disease, new data has revealed.

  • JLS take on new mission to help beat cancer

    Updated: 2012-12-07 00:01:00
    MOBO and Brit Award winning group JLS and world leading charity Cancer Research UK have joined forces to re-launch the JLS Foundation this December, to coincide with Childhood Cancer Awareness Month. The Foundation’s aim is to help fund Cancer Research UK's vital research specifically into cancers that affect children, teenagers and young adults aged 0-24 within the UK, to help bring forward the day when all cancers are cured.

  • Study confirms fewer, bigger doses of radiotherapy benefit breast cancer patients

    Updated: 2012-12-06 13:30:00
    A lower total dose of radiotherapy, delivered in fewer, larger treatments, is as safe and effective at treating early breast cancer as the international standard dose, according to the 10-year follow-up results of a major Cancer Research UK trial presented at the 2012 CTRC-AACR San Antonio Breast Cancer Symposium today (Thursday).

  • National audit reveals improvements in lung cancer care

    Updated: 2012-12-05 16:38:00
    Lung cancer care in the UK is continuing to make incremental improvements, according to a major national audit.

  • Trial reveals 10 years of tamoxifen halves later deaths from commonest kind of cancer

    Updated: 2012-12-05 13:30:00
    Ten years of tamoxifen treatment can approximately halve the number of deaths from the most common form of breast cancer during the second decade after diagnosis, according to the results of the Cancer Research UK- funded ATLAS trial published in the Lancet today.

  • Britons want bowel cancer screening recommendation

    Updated: 2012-12-05 00:01:00
    Britons want a recommendation from the NHS on whether to attend bowel cancer screening, along with all the information on benefits and risks, according to research published in the British Journal of Cancer today.

  • Study backs flexi-scope for bowel screening

    Updated: 2012-12-04 23:00:00
    Using an internal camera called a flexi-scope to screen for signs of bowel cancer can greatly reduce deaths from the disease, according to a review of previous evidence.

  • Targeted Therapy Leads 2012 Cancer Advances

    Updated: 2012-12-03 22:09:02
    Targeted therapies for metastatic HER2-positive breast cancer are among this year's top advances in oncology, according to the American Society of Clinical Oncology.

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